Diagnostic significance of colloid body deposition in direct immunofluorescence
نویسندگان
چکیده
منابع مشابه
Clinical Significance of Positive Platelet Immunofluorescence Assay in Adult Immune Thrombocytopenia: a Cross Sectional Study
Background: Immune thrombocytopenia is a hematologic disorder characterized by low platelet count and variable bleeding manifestations due to immune-mediated platelet destruction and/or suppression of platelet production. This study was performed to evaluate characteristics and clinical presentations of adult patients with immune thrombocytopenia and to explore the clinical value of platelet an...
متن کاملDirect and indirect immunofluorescence.
Immunofluorescence is a valuable auxiliary diagnostic tool for autoimmune bullous diseases and inflammatory disorders, since their clinical and histopathologic findings may be inconclusive. It is a feasible laboratory method that requires experienced technicians and detects in situ and circulating immune deposits that may be involved in the pathogenesis of such skin diseases.
متن کاملEvaluation of clinical and histopathologic/direct immunofluorescence diagnosis in autoimmune vesiculobullous dermatitis: utility of direct immunofluorescence.
OBJECTIVE Autoimmune bullous diseases are heterogeneous diseases and the differentiation between the various bullous disease is important for treatment and prognosis. Direct immunofluorescence microscopy is still the gold standard in differentiating these diseases. Our aim was to determine the diagnostic accordance between clinical and histopathological/direct immunofluorescence diagnosis of pa...
متن کاملTechniques of immunofluorescence and their significance.
1) Skin or mucosal biopsy specimens are usually obtained by 3-5 mm punch or surgical biopsy. 2) Biopsy specimens are snap frozen. If there is a delay between biopsy and snap freezing, the specimen should be kept in cold saline. 3) Frozen 4-6μ sections are cut on a cryostat and placed on a glass slide before being air-dried for 15 minutes. 4) After rinsing in phosphate buffered saline (PBS), pH ...
متن کاملFalse-negative direct immunofluorescence testing in vancomycin-induced linear IgA bullous dermatosis: a diagnostic pitfall.
False-negative direct immunofluorescence testing in vancomycin-induced linear IgA bullous dermatosis: a diagnostic pitfall" (2016).
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology, Venereology, and Leprology
سال: 2010
ISSN: 0378-6323
DOI: 10.4103/0378-6323.66583